KLINIKO-METABOLIC ASPECTS OF THE HEAVY CURRENT OF SHARP INFECTIONS OF THE TOP RESPIRATORY WAYS

Abstract

Purpose. An estimation of character and intensity of metabolic processes in lymphocytes sick осртыми respiratory virus infections on changes of activity of endocellular enzymes depending on weight of a clinical course. Methods. Indicators of enzymes of lymphocytes of 52 patients at the age from 18 till 42 years with the diagnosis a sharp respiratory virus infection were defined. Results. At the height of disease distinctive feature of an intensification of reactions pentozofasfatis a cycle and glikolisis isn'ted, and also at substantial increase of functional loading on cages, there is a considerable decrease in intensity of reactions of the initial stage of a cycle трикарбоновых acids that reduces power efficiency of a cycle, and intensive receipt of metabolites by cycle supply threekarbonis acids substrata with amino acidis an exchange, provides the raised transport of amino acids in lymphocytes. Conclusion. Without the raised possibilities of a lymphocyte to prolesferis, citocinis, antibodies and other humoral factors development of the immune answer adequate to conditions, shown by infectious aggression is impossible for synthesis. Scope of results. Practical public health services, infectious diseases, immunology.