Creatine supplementation spares muscle glycogen during high intensity intermittent exercise in rats
Keywords
SportsGV557-1198.995
Recreation. Leisure
GV1-1860
Geography. Anthropology. Recreation
G
DOAJ:Sports Science
DOAJ:Social Sciences
Nutrition. Foods and food supply
TX341-641
Home economics
TX1-1110
Technology
T
DOAJ:Nutrition and Food Sciences
DOAJ:Agriculture and Food Sciences
Sports medicine
RC1200-1245
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<p>Abstract</p> <p>Background</p> <p>The effects of creatine (CR) supplementation on glycogen content are still debatable. Thus, due to the current lack of clarity, we investigated the effects of CR supplementation on muscle glycogen content after high intensity intermittent exercise in rats.</p> <p>Methods</p> <p>First, the animals were submitted to a high intensity intermittent maximal swimming exercise protocol to ensure that CR-supplementation was able to delay fatigue (experiment 1). Then, the CR-mediated glycogen sparing effect was examined using a high intensity intermittent sub-maximal exercise test (fixed number of bouts; six bouts of 30-second duration interspersed by two-minute rest interval) (experiment 2). For both experiments, male Wistar rats were given either CR supplementation or placebo (Pl) for 5 days.</p> <p>Results</p> <p>As expected, CR-supplemented animals were able to exercise for a significant higher number of bouts than Pl. Experiment 2 revealed a higher gastrocnemius glycogen content for the CR <it>vs</it>. the Pl group (33.59%). Additionally, CR animals presented lower blood lactate concentrations throughout the intermittent exercise bouts compared to Pl. No difference was found between groups in soleus glycogen content.</p> <p>Conclusion</p> <p>The major finding of this study is that CR supplementation was able to spare muscle glycogen during a high intensity intermittent exercise in rats.</p>Date
2010-01-01Type
ArticleIdentifier
oai:doaj.org/article:8f9aed76620d43c2b95470ba0209224e10.1186/1550-2783-7-6
1550-2783
https://doaj.org/article/8f9aed76620d43c2b95470ba0209224e