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Articaine and mepivacaine efficacy in postoperative analgesia for lower third molar removal: a double-blind, randomized, crossover study

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Author(s)
Colombini, Bella L.
Modena, Karin C.S.
Calvo, Adriana M.
Sakai, Vivien T.
Giglio, Fernando P. M.
Dionísio, Thiago J.
Trindade Jr., Alceu S.
Lauris, José R. P.
Santos, Carlos F.
Contributor(s)
Universidade Estadual Paulista (UNESP)
Keywords
articaine
local anesthetic agent
mepivacaine
nonsteroid antiinflammatory agent
piroxicam
adolescent
adult
clinical trial
controlled clinical trial
controlled study
crossover procedure
dental anesthesia
double blind procedure
female
human
local anesthesia
male
methodology
molar tooth
postoperative pain
randomized controlled trial
tooth disease
tooth extraction
Adolescent
Adult
Anesthesia, Dental
Anesthesia, Local
Anesthetics, Local
Anti-Inflammatory Agents, Non-Steroidal
Carticaine
Cross-Over Studies
Double-Blind Method
Female
Humans
Male
Mepivacaine
Molar, Third
Pain, Postoperative
Piroxicam
Tooth Extraction
Tooth, Impacted
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URI
http://hdl.handle.net/20.500.12424/1860153
Online Access
https://dx.doi.org/10.1016/j.tripleo.2005.09.003
http://hdl.handle.net/11449/69014
Abstract
Objective: Comparison of the clinical efficacy of 4% articaine in relation to 2% mepivacaine, both with 1:100,000 epinephrine, in the prevention of postoperative pain after lower third molar removal. Study design: Twenty patients underwent removal of bilateral lower third molars under local anesthesia (articaine or mepivacaine) in 2 separate appointments, in a double-blind, randomized, and crossed manner. Objective and subjective parameters were recorded for paired comparison of postoperative courses. Results: Duration of analgesia provided by articaine and mepivacaine was 198.00 ± 25.86, and 125.40 ± 13.96 min, respectively (P = .02), whereas the duration of anesthesia was 273.80 ± 15.94 and 216.85 ± 20.15 min, respectively (P = .06). Both solutions exerted no important effects upon arterial pressure, heart rate, or oxygen saturation (P > .05). Conclusions: Articaine provides a longer period of analgesic effect and a tendency for a longer period of anesthesia as compared to mepivacaine. The presence of a vasoconstrictor agent in local anesthetic solutions does not seem to influence hemodynamic parameters during lower third molar removal in healthy subjects. © 2006 Mosby, Inc. All rights reserved.
Date
2014-05-27
Type
info:eu-repo/semantics/article
Identifier
oai:repositorio.unesp.br:11449/69014
http://dx.doi.org/10.1016/j.tripleo.2005.09.003
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, v. 102, n. 2, p. 169-174, 2006.
1079-2104
http://hdl.handle.net/11449/69014
10.1016/j.tripleo.2005.09.003
2-s2.0-33746225379
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    Treatment of traumatic dental injuries: evaluation of knowledge among Italian dentists

    Re, D; Augusti, D; Paglia, G; Augusti, G; Cotti, E (2014)
    The aim of this study was to evaluate the degree of knowledge in the management of different scenarios of dental trauma in a population of Italian dentists.
  • Thumbnail

    Articaine and mepivacaine efficacy in postoperative analgesia for lower third molar removal: a double-blind, randomized, crossover study

    Universidade Estadual Paulista (UNESP); Colombini, Bella L.; Modena, Karin C.S.; Calvo, Adriana M.; Sakai, Vivien T.; Giglio, Fernando P. M.; Dionísio, Thiago J.; Trindade Jr., Alceu S.; Lauris, José R. P.; Santos, Carlos F. (2014-05-27)
    Objective: Comparison of the clinical efficacy of 4% articaine in relation to 2% mepivacaine, both with 1:100,000 epinephrine, in the prevention of postoperative pain after lower third molar removal. Study design: Twenty patients underwent removal of bilateral lower third molars under local anesthesia (articaine or mepivacaine) in 2 separate appointments, in a double-blind, randomized, and crossed manner. Objective and subjective parameters were recorded for paired comparison of postoperative courses. Results: Duration of analgesia provided by articaine and mepivacaine was 198.00 ± 25.86, and 125.40 ± 13.96 min, respectively (P = .02), whereas the duration of anesthesia was 273.80 ± 15.94 and 216.85 ± 20.15 min, respectively (P = .06). Both solutions exerted no important effects upon arterial pressure, heart rate, or oxygen saturation (P > .05). Conclusions: Articaine provides a longer period of analgesic effect and a tendency for a longer period of anesthesia as compared to mepivacaine. The presence of a vasoconstrictor agent in local anesthetic solutions does not seem to influence hemodynamic parameters during lower third molar removal in healthy subjects. © 2006 Mosby, Inc. All rights reserved.
  • Thumbnail

    Lay knowledge of physical education teachers about the emergency management of dental trauma in Hong Kong

    Wong, TKS; Chan, AWK; Cheung, GSP (Blackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/EDTDenmark, 2010-09-06)
    The purpose of this study was to investigate the knowledge of a group of physical education (PE) teachers about the emergency management of dental trauma in Hong Kong. A postal questionnaire was sent to PE teachers in 100 randomly selected secondary schools in Hong Kong. A total of 166 teachers from 65 schools responded. Results show that a majority of the respondents have received formal teaching training (98.8%). While all but one teacher had received formal first aid training, only eight of them recalled that they had received advice on the management of dental trauma. Concerning the management of tooth fracture, 118 respondents (71.1%) gave an appropriate answer. In contrast, only 29 teachers (17.5%) were able to indicate the appropriate management for an avulsed tooth. Over 60% (102) of the respondents indicated it was "very urgent" to seek professional assistance if a permanent tooth has been avulsed, but they had little knowledge of the correct procedures for replanting or transporting avulsed teeth. Only 15 respondents (9%) pointed out that milk was the medium of choice for transporting avulsed teeth. Finally, over 90% (157) of respondents indicated that they had never received advice on the emergency procedures for the management of dental avulsion. The present study showed that the level of lay knowledge of management of dental injuries in a selection of PE teachers in Hong Kong is inadequate and educational campaigns are necessary to improve their emergency management of dental injuries. © Munksgaard, 2001.
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