Author(s)
Steelman, Victoria M.Keywords
Creutzfeldt-Jakob SyndromeEducation
Continuing (Credit)
Creutzfeldt-Jakob Syndrome -- Etiology
Creutzfeldt-Jakob Syndrome -- Transmission
Creutzfeldt-Jakob Syndrome -- Prevention and Control
Organ Transplantation
Occupational Exposure -- Prevention and Control
Bacterial Contamination
Equipment Contamination
Surgical Instruments
Sterilization and Disinfection
Nursing
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http://works.bepress.com/victoria_steelman/28Date
1997-07-01Type
textIdentifier
oai:works.bepress.com:victoria_steelman-1027http://works.bepress.com/victoria_steelman/28
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The new variant of the Creutzfeldt-Jakob disease accounts for no relative increase of the Creutzfeldt-Jakob disease mortality rate in the United Kingdom; this fits ill with the new variant being the consequence of consumption of food infected with the agent of Bovine Spongiform EncephalopathyHénaut Alain; Laprevotte Ivan (BMC, 2003-08-01)<p>Abstract</p> <p>Background</p> <p>A new variant of Creutzfeldt-Jakob disease was described in the United Kingdom. It is often claimed that it is caused by consumption of food infected with the agent of bovine spongiform encephalopathy. However, this remains open to question because the number of cases of the variant is, at the present time, less than would be expected from a major food-borne source.</p> <p>Discussion</p> <p>The EUROCJD cooperative study presents currently available epidemiological data of Creutzfeldt-Jakob disease and its new variant, for nine European countries plus Australia and Canada. Unexpectedly, for the United Kingdom where all but a few cases of the new variant have been reported, these cases have to be included in the incidence curve of the sporadic forms of the disease in order to obtain the best fit with the median curve from all the countries. This variant could be merely a rare clinical phenotype within the sporadic disease. The published clinical and experimental data which suggest that it is linked with bovine spongiform encephalopathy, lead us to propose that this link could be a common etiological origin other than consumption of bovine infected food. In any case, public health recommendations hold and further investigation is required.</p> <p>Summary</p> <p>The lack of a relative increase of the Creutzfeldt-Jakob-disease mortality rate in the United Kingdom, does not fit well with the new variant being the consequence of consumption of food infected with the agent of bovine spongiform encephalopthy.</p>
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Variant Creutzfeldt–Jakob disease and the Quebec blood supplyGermain, Marc; Décary, Francine (Canadian Medical Association, 2000)"In the mid-1980s bovine spongiform encephalopathy (BSE) was recognized as an emerging prion disease of epidemic proportions in the United Kingdom. In April 1996, researchers in the UK announced that they had identified 11 patients with a new form of spongiform encephalopathy, now called variant Creutzfeldt–Jakob disease (vCJD).1 Since then, more than 70 definite or probable cases of vCJD have been identified, all of them in the UK, except 1 in Ireland and 3 in France (1 of which has not been officially confirmed).2 Although definite proof is still lacking, current evidence indicates that these human cases were infected with the same strain of prion that causes BSE. In all likelihood the infections resulted from the ingestion of BSE-contaminated food. "
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Notifying patients exposed to blood products associated with Creutzfeldt–Jakob diseaseCaulfield, Timothy (Canadian Medical Association, 1997)"Over the past decade, institutions providing blood transfusion services have been under intense public scrutiny. Undertakings such as the Krever inquiry have sensitized the public to transfusion-related issues. In this climate of anxious uncertainty, the spectre of yet another serious illness transmissible through blood products arose in July 1995, when Health Canada and the Canadian Red Cross Society Blood Services initiated an urgent recall of blood fractionation products prepared from the plasma of a donor who subsequently died of Creutzfeldt–Jakob disease (CJD). The Canadian Red Cross Society issued a recommendation to health care institutions that recipients of recalled blood products be identified, notified and counselled."