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AbstractEthics, which constitutes principles that guide human conduct, deserves particular attention in this era of the Anthropocene, when human actions greatly influence ecology. Renaissance humans have hegemonised humanistic ethics of living and interacting with the world since the Enlightenment. While exalting human exceptionalism, humanism has relegated all other forms of existence to a subservient taxonomy, categorising them as raw material for human empowerment. The self-exalted autonomous subject, homo sapiens, faces the threat of extinction in the wake of unprecedented and violent ecological reactions. The exponential growth of the agency of intelligent machines also calls to question the autonomous human agency propagated by humanism. A paradigm shift is the moment’s need; this paper suggests posthuman ethics as an alternative. The new worldview, post-humanism, places the homo sapiens in relation to the rest of the universe. Philosophical post-humanism, proposed by Francesca Ferrando, foregrounds posthuman ethics that are post-humanistic, post-anthropocentric, and post-dualistic. They form a roadmap towards a sustainable future.