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AbstractThis paper discusses the teaching- learning process of mathematical subjects made accessible to visually disabled students. It aims to provide users a friendly vocal interface with computer and allow visually impaired people to use the computer. It focuses on the issues that arise from representation, encoding and manipulation of mathematics in electronic media. Professionals use tools like LaTeX that result in encoding of mathematics, symbols and expressions. A well encoded MathML expression can be evaluated in a computer algebra system rendered in a web browser. Some approaches for achieving the transformations from MathML to speech output are mentioned in this paper. A Text-To-Speech (TTS) system that supports JSML is responsible for rendering a document as spoken output. The challenge for educational institutions is, as they increase the use of e learning, they must apply these techniques in a way that does not introduce unnecessary barriers to disabled learners.