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Evaluation of Demographic, Histopathologic and Radiological Features of Thyroid Cancer Patients

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Author(s)
Değer, Özgür
Ersoy, İsmail Hakkı
Aksu, Oğuzhan
Köroğlu, Banu Kale
Çiriş, İbrahim Metin
Tamer, Mehmet Numan
Keywords
Thyroid Cancer; Patients; Demography; Histopathology; Epidemiology; Ultrasonography.
Tiroid Kanseri; Hastalar; Demografi; Histopatoloji; Epidemiyoloji; Ultrasonografi.

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URI
http://hdl.handle.net/20.500.12424/919506
Online Access
http://dergipark.ulakbim.gov.tr/totmd/article/view/5000100051
Abstract
Aim: Our aim of this retrospective study was to evaluate the demographic, histopathologic and radiological features of thyroid cancer patients. Material and Methods: In our study 129 thyroid cancer patients were divided into two groups: group 1 (tumor size <1cm) and group 2 (tumor size >1 cm). Parameters were age, gender, preoperative thyroid function test results, findings of nodule structure, nodule echogenicity and border features, presence of microcalcification and halo and anterioposterior diameter in preoperative thyroid ultrasonography, presence of radioactive iodine therapy, postoperative thyroglobulin values, postoperative diagnosis, histological type and size of the tumor, presence of multifocality and bilaterality, presence of invasion and recurrence after therapy. Results: 27 (20.9%) of the patients were male and the remaining 102 (79.1%) patients were female. The preoperative average age was 44.8±14.4 years. There were no significant differences between two groups when compared to their age, fT3, fT4, TSH, TG, anti-TPO, anti-TG, supplementary operation, postoperative aphonia, hypocalcemia symptoms, multifocality of the tumor, bilateral tumor presence, nodule halo, anterioposterior diameter, recurrence, results of thyroid fine needle aspiration biopsy, structure and echogeneity of the nodule and pre- and postoperative diagnostic features. Most common preoperative histopathological diagnosis was suspicious malignancy (39.6%), whereas the most common postoperative diagnosis was papillary carcinoma (88.5%). Conclusion: Extensive studies will enable the approaches with a result to minimize the disease related mortality and enable the early diagnosis of thyroid cancers. Key words: Thyroid Cancer; Patients; Demography; Histopathology; Epidemiology; Ultrasonography.
Amaç: Bu retrospektif çalışmada tiroid kanserli hastaların demografik, histopatolojik ve radyolojik özellikleri değerlendirildi. Gereç ve Yöntemler: Tiroid kanserli 129 hastanın alındığı çalışmada hastalar 2 gruba ayrıldı: grup 1 tümör boyutu 1 cm'den küçük olan hastalar ve grup 2 tümör boyutu bir cm'den büyük olan hastalar. Yaş, cinsiyet, preoperatif tiroid fonksiyon test sonuçları, tiroid ultrasonografisinde nodül yapısı, nodül ekosu ve kenar özelliği, mikrokalsifikasyon ve halo varlığı, anteroposterior çapı, hastanın radyoaktif iyot tedavisi alıp almadığı, postoperatif tiroglobulin değerleri, postoperatif tanı, tümörün histolojik tipi, boyutu, multifokalite ve bilateralite durumu, invazyon varlığı ve tedavi sonrası nüks varlığı değerlendirildi. Bulgular: Hastaların 27'si (%20.9) erkek ve 102'si (%79.1) kadındı. Hastaların preoperatif yaş ortalaması 44.8±14.4 yıl olarak saptandı. Her iki grup arasında yaş, fT3, fT4, TSH, TG, anti-TPO, anti-TG, tamamlayıcı operasyon, postoperatif ses kısıklığı ve hipokalsemi belirtileri, tümörün multifokal olması, tümörün bilateral yerleşimi, nodül halosu, nodül anteroposterior çapı, nüks, tiroid ince iğne aspirasyon biyopsi sonuçları, nodül yapısı ve nodül ekosu, bakımından anlamlı fark saptanmadı. En sık görülen preoperatif histopatolojik tanı şüpheli malignite (%39.6) iken, postoperatif en sık tanı papiller karsinom (%88.5) olarak rapor edildi. Sonuç: Geniş çaplı araştırmalar tiroid kanserlerinin erken tanıları ve hastalığa bağlı mortalitelerini en az düzeye indirebilecek tedavi yaklaşımlarının gelişmesine imkan sağlayacaktır. Anahtar kelimeler: Tiroid Kanseri; Hastalar; Demografi; Histopatoloji; Epidemiyoloji; Ultrasonografi.
Date
2013-06-01
Type
info:eu-repo/semantics/article
Identifier
oai:dergipark.ulakbim.gov.tr:record/161984
http://dergipark.ulakbim.gov.tr/totmd/article/view/5000100051
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